2024 Refractoriness to treatment

Refractoriness to treatment

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August undefined, 2024

WebNov 26, 2024 · When drug treatment ends, oppositional processes may encounter no more resistance, resulting in the appearance of new withdrawal symptoms, rebound … Webtient demonstrates initial refractoriness to conventional doses of medication, the dose should be titrated to the maximum tolerable within the recommended range and …

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WebOct 17, 2024 · Furthermore, ‘refractoriness to treatment’ is a clear-cut moment during haemorrhage that may allow for differentiation between women who will stop bleeding … WebOct 17, 2024 · The absence of a uniform and clinically relevant definition of severe postpartum haemorrhage hampers comparative studies and optimization of clinical management. The concept of persistent postpartum haemorrhage, based on refractoriness to initial first-line treatment, was proposed as an alternative to common definitions that … money\u0027s worth

Refractoriness of aggressive behaviour to pharmacological treatment …

WebNov 20, 2024 · Refractoriness to a MM agent was defined as lack of objective response, progression while receiving therapy or within 60 days of the last dose as standardized by the International Myeloma Working... WebFeb 26, 2024 · Citation 9 These detection methods, however, require at least 1–2 rounds of radioactive iodine (RAI) treatment to make the final diagnosis of RAIR. In patients with disease progression and non-tumoricidal RAI uptake, the diagnosis is delayed even longer. ... Citation 30 All candidates with RAI refractoriness were categorized into the RAIR ... WebPlatelet transfusion refractoriness is the repeated failure to achieve the desired level of blood platelets in a patient following a platelet transfusion. The cause of refractoriness may be either immune or non-immune. Among immune-related refractoriness, antibodies against HLA antigens are the primary cause. money\u0027s-worth 24

Clinical characteristics of women captured by extending the …

Refractoriness - definition of refractoriness by The Free …

WebMar 16, 2024 · Refractoriness to platelet transfusions. Avoiding platelet transfusions as much as possible is important in alloimmunized patients. Prophylactic transfusions are … WebNov 11, 2024 · This topic covers the logistics of platelet use and the indications for platelet transfusion in adults. The approach to the bleeding patient, refractoriness to platelet transfusion, and platelet transfusion in neonates are discussed separately. Evaluation of bleeding – (See "Approach to the adult with a suspected bleeding disorder" .) money\u0027s-worth 6uWebFeb 13, 2024 · Current treatment of ITP is not strictly regimented. 7 First-line therapy usually consists of steroids (high-dose dexamethasone or prednisone) or IV immunoglobulin (IVIG), or even a combination of both for certain patients. Second-line treatment primarily includes thrombopoietin receptor agonists (TPO-RAs) and rituximab, with splenectomy deferred … money\\u0027s-worth 6u

"WebJan 17, 2024 · Ibrutinib-refractoriness is determined by progression on repeated evaluations so that an effective therapy is not abandoned. There are two forms of ibrutinib relapse: progressive CLL and histologic transformation. Ibrutinib should not be discontinued in a relapsing patient without a new treatment plan in place. " - Refractoriness to treatment

Refractoriness to treatment

$Platelet transfusion refractoriness - Wikipedia$

WebAmong patients with refractoriness, rFVIIa was considered effective in 94.9% of bleeding episodes and 98.6% of surgical procedures. The recommended dosing for severe bleeding episodes is 90 µg/kg every 2–6 hours and for surgery 90 µg/kg every 2 hours. 16. Table 1 Adjudicator evaluation of GTR rFVIIa efficacy data. Webre· frac· to· ry ri-ˈfrak-t (ə-)rē Synonyms of refractory 1 : resisting control or authority : stubborn, unmanageable 2 a : resistant to treatment or cure a refractory lesion b : …

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WebApr 9, 2024 · One of the most characteristic features of chromoblastomycosis is its refractoriness to treatment. Treatment options include oral itraconazole (as monotherapy or with oral 5-flucytosine... WebMay 1, 2001 · Refractoriness to infused platelets becomes a major clinical problem for many patients with acute myeloid leukemia (AML). Inadequate post-transfusion platelet count increments can be due to a ...

WebDec 18, 2024 · Treatment of Refractory GTS. As stated above, refractoriness in GTS is highly determined by the response to the evidence-based treatments. In the recently published, evidence-based recommendations by the American Academy of Neurology (AAN) (5, 7), the authors revised the available treatments for GTS.A multidisciplinary panel of experts … WebIn this issue of BJH, Mohyuddin et al. examined the inclusion criteria of active trials on CART cells, bispecific antibodies or antibody-drug conjugates and found that the vast majority of studies still contain number of lines of treatment with or …

WebApr 8, 2024 · Axonal damage in the C-fibers leading to evoked potentials/increased refractoriness translated to monotonic increase/decrease of all quantitative pain markers (Figure 4 and Figure 5). However, the N C marker (that counts the number of times the pain signal crosses the typical π thresh = 25 Hz threshold) behaves very differently for the ... WebAug 7, 2024 · Refractoriness of aggressive behaviour to pharmacological treatment: cortical thickness analysis in autism spectrum disorder. Flavia Venetucci Gouveia, Jürgen …

WebRefractoriness. Table 10 shows how refractoriness improves at least up to the mullite composition, and there is a steady improvement in hot strength through the range, while …

WebSep 27, 2024 · Refractoriness to treatment is a substantial clinical concern. Several pharmacologic and other somatic interventions have been tried with variable results. The first step after the diagnosis of tardive dystonia induced by antipsychotic medications or other drugs is to taper and then discontinue the causative drugs. Many times, a severe ... money\\u0027s-worth 1fWebJan 16, 2014 · Refractoriness to oral iron treatment was defined as a hemoglobin (Hb) increment of <1 g/dL after 4 to 6 weeks of therapy at a daily dose of at least 100 mg of … money\u0027s-worth 5tWebFeb 7, 2024 · Herpes proctitis is treated with acyclovir 400 mg oral three times daily or valacyclovir 1 gram twice daily or famciclovir 250 mg three times daily for 7 to 10 days. The course of treatment may be extended if … money\\u0027s-worth 7uWebMay 12, 2024 · TREATMENT OF BLEEDING — Major bleeding (or minor bleeding expected to progress to major bleeding) requires a coordinated approach, especially in individuals with platelet refractoriness. Urgent involvement of the transfusion medicine service and … money\u0027s-worth 4rWebBased on the case reported by Siemons et al. in 1987 describing the efficacy of intravenous Anti‐D treatment for immune refractoriness to platelet transfusion in an aplastic anaemia patient, 10 we started using Anti‐D treatment, first in one patient with myelodysplastic syndrome who was RhD‐positive and refractory to platelet transfusion ... money\u0027s-worth 7uWebDec 4, 2024 · Refractoriness can be caused by immune and nonimmune factors, with nonimmune factors responsible for 60% to 80% of cases. 1 Immune factors, which play a … money\\u0027s-worth 5tWebApr 4, 2024 · However, because several molecular targeted agents, including sorafenib, are now available based on their proven treatment efficacy from several randomized trials , the concept of TACE refractoriness was proposed to prevent the deterioration of liver function or stage progression during repeated TACE sessions [15, 24–26]. money\\u0027s-worth 77