WebCyclophosphamide is an oxazaphosphorine that contributes alkyl groups to DNA, forming covalent linkages. It depletes T and B cells and suppresses antibody production. It is metabolized to 4-hydroxycyclophosphamide and its tautomer aldophosphamide by liver cytochrome P450 enzyme. WebI-Phosphamide side effects and Toxicity. LD 50 (mouse) = 390-1005 mg/kg, LD 50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

A Spiro Phosphamide Catalyzed Enantioselective Proton Transfer …

WebPhosphoramide H6N3OP CID 123317 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety ... WebFischer S, et al. Aktuelles bei der Lungentransplantation 138 Med Klin 2002;97:137–43 (Nr. 3) ÜBERSICHT Lungenerkrankungen, das α-1-Anti-trypsin-Mangel-Emphysem, die idio- cobalt strike 4.5 download

Cyclophosphamide - Wikipedia

Cyclophosphamide (CP), also known as cytophosphane among other names, is a medication used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and … See more Cyclophosphamide is used to treat cancers and autoimmune diseases. It is used to quickly control the disease. Due to its toxicity, it is replaced as soon as possible by less toxic drugs. Regular and frequent laboratory … See more Like other alkylating agents, cyclophosphamide is teratogenic and contraindicated in pregnant women (pregnancy category D) except for life-threatening … See more Oral cyclophosphamide is rapidly absorbed and then converted by mixed-function oxidase enzymes (cytochrome P450 system) … See more As reported by O. M. Colvin in his study of the development of cyclophosphamide and its clinical applications, Phosphoramide mustard, one of the principal toxic … See more Adverse drug reactions from cyclophosphamide are related to the cumulative medication dose and include chemotherapy-induced nausea and vomiting See more The main effect of cyclophosphamide is due to its metabolite phosphoramide mustard. This metabolite is only formed in cells that have low levels of ALDH. Phosphoramide … See more The abbreviation CP is common, although abbreviating drug names is not best practice in medicine. See more WebPhosphoramidon is a chemical compound derived from cultures of Streptomyces tanashiensis. It is an inhibitor of the enzyme thermolysin, [2] of the membrane metallo … cobaltstrike beacon staging server文件下载