2024 Phenoscanner gwas database

Phenoscanner gwas database

Author: lgrm

August undefined, 2024

WebEighteenth were significantly associated about at least the additional traits (p ≤ 5 × 10 −8) in the PhenoScanner database, especially anthropometric, vessels, ... We kept PhenoScanner GWAS connection results because an p-value < 5 × … Web1. nov 2024 · RegulomeDb, GWAS Central, GTEx and PhenoScanner depicted the involvement of ULK1 gene in various parts of brain leading to various mental disorders. The interaction of ULK1 gene and its pathway analysis showed that ULK1 gene interacts with various other genes like ATG, mTOR, RPTOR and many more involved in autophagy …

Causal associations of anthropometric measurements with …

Web30. jan 2024 · The exposure and outcome GWAS provided SNP effects and corresponding standard errors . We filtered out palindromic SNPs with intermediate allele frequencies after harmonizing exposure and outcome data . We used the PhenoScanner V2 database to detect potential pleiotropy among the SNPs included in this study . Genetic variants that … WebBidirectional causality between stroke and myocardial infarction: a Mendelian randomization study in american men sizes 40

Frontiers Causal Association of Coffee Consumption and Total, …

Web5. júl 2024 · In addition to the identification of risk genes from GWAS, we identified miRSNPS from the MSDD database and found that hsa-miR-223 and hsa-miR-23a were associated with genetic variants such as rs1044165 and rs3745453, respectively . WebAs of , the GWAS Catalog contains publications, top associations and full summary statistics. GWAS Catalog data is currently mapped to Genome Assembly and dbSNP Build … Web6. dec 2024 · A total of 465 significant associations (P<0.01) were found using GWAS analysis in PhenoScanner. rs191188930 was significantly associated with other diseases or phenotypes other than cardiotoxicity, including acute pericarditis, aortic aneurysm and dissection, other necrotizing vasculopathies, urticaria, ascites and tubulo-interstitial … inaul background

PhenoScanner V2: an expanded tool for searching human genotype

Assessment Causality in Associations Between Serum Uric Acid …

WebJIA GWAS summary statistics were acquired from the recently updated meta-analysis of 6056 patients with all JIA subtypes and 25,086 controls of European descent. 22 Detailed and clear descriptions, including the study procedure, ... With the PhenoScanner database ... WebA meta-analysis of twin studies and a Swedish population-based study estimated the heritability of schizophrenia ranged from 64% to 81%. 14,15 A large genome-wide association study (GWAS) identified 128 single nucleotide polymorphisms (SNPs) significantly associated with schizophrenia which explained approximately 3.4% of the … inaul characteristicsWeb15. okt 2016 · PhenoScanner is a curated database of publicly available results from large-scale genetic association studies. This tool aims to facilitate 'phenome scans', the cross-referencing of genetic variants with many phenotypes, to help aid understanding of disease pathways and biology. The database currently contains over 350 million association ... inaul gown

"Webphenoscanner: PhenoScanner Description The phenoscanner function queries the PhenoScanner database of genotype-phenotype associations from inside R. Usage … " - Phenoscanner gwas database

Phenoscanner gwas database

Causal association between asthma and periodontitis: A …

http://ebi.ac.uk/gwas/ WebPhenoScanner A database of human genotype-phenotype associations Search Catalogue: p -value: Proxies: r 2: Build: Examples: rs10840293 , chr11:9751196 , chr11:9500000 … Introduction. PhenoScanner is a curated database holding publicly available … PhenoScanner is a curated database holding publicly available results from … A database of human genotype-phenotype associations Query: SNP Gene Region … PhenoScanner (current) About; Documentation . Information; Studies; … The phenoscanner R package allows users to query the PhenoScanner database … A database of human genotype-phenotype associations. ... Datasets. Some of the … We would like to thank Dr Andrew Johnson for allowing us to host results from the … A database of human genotype-phenotype associations. Updates. 31/02/2024 - …

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Web17. jún 2016 · PhenoScanner is a curated database of publicly available results from large-scale genetic association studies. This tool aims to facilitate ‘phenome scans’, the cross … Web15. nov 2024 · PhenoScanner is a curated database of publicly available results from large-scale genetic association studies in humans. This online tool facilitates ‘phenome scans’, …

Web9. feb 2024 · Based on summary statistics from publicly available genome-wide association studies (GWAS) database, we detected the genetic correlation between serum 25OHD levels and DN by a two-sample Mendelian randomization (MR) analysis. WebGWAS Central contains 70,566,447 associations between 3,251,694 unique SNPs and 1,451 unique MeSH disease/phenotype descriptions. GWAS Central data content is available in its entirety to researchers as part of a collaboration. To discuss your requirements, send an email to [email protected].

WebR语言MendelianRandomization包 phenoscanner函数使用说明. phenoscanner函数从R内部查询基因型-表型关联的phenoscanner数据库。. snpquery : 单核苷酸多态性的载体。. genequery : 基因名称的载体。. regionquery : 基因组区域的载体。. catalogue : 要搜索的目录（选项：None、GWAS、eQTL、pQTl ... Web15. mar 2024 · To assess whether PA is related to OC, we identified genetic statistics from the EOC GWAS conducted by the Ovarian Cancer Association Consortium (OCAC). 22 All 66,450 samples were of European descent, of which 25,509 were OCs. 22 The numbers of histological subtypes of OC are presented in Supplemental Table S6. Statistical analysis

WebThis GWAS evaluated three continuous-leisure sedentary behavior phenotypes: (1) self-reported hours spent watching television per day; (2) self-reported hours spent using a computer (excluding work use) per day; and (3) self-reported hours spent driving per day.

WebConsidering the important roles of gut metabolites in microbiota-host crosstalk, we also leveraged summary-level data from a GWAS of the human metabolome conducted among European-descent subjects (TwinsUK and KORA, N = 7824). The GWAS tested all 486 metabolite concentrations present in both datasets at each SNP. inaul is the famousWebDental caries and periodontitis account for a vast burden of morbidity and healthcare spending, yet their genetic basis remains largely uncharacterized. Here, we identify self-reported dental disease proxies which have similar underlying genetic inauguration women\\u0027s fashionWebBackgroundThe causal association between coffee consumption and the risk of OA is limited. This study was conducted to identify the potential causal effects of coffee consumption on total, knee, hip, and self-reported OA.MethodsGenome-wide association studies (GWAS) of OA were derived from the UK Biobank, comprising 50,508 participants … in american money how much is a shillingWeb10. sep 2024 · Our resource, PhenomeXcan, synthesizes 8.87 million variants from genome-wide association study summary statistics on 4091 traits with transcriptomic data from 49 tissues in Genotype-Tissue Expression v8 into a gene … in american the common greeting isWeb21. feb 2024 · ScienceOpen: research and publishing network For Publishers. Discovery Metadata Peer review Hosting Publishing inauguredWebthe GWAS Catalog), while there were >50 000 genetic associations with coronary heart disease with P < 1 10 5 across the genome (compared with 1092 associations found by the GWAS Catalog). 4 Conclusion PhenoScanner V2 is a large curated database of human genotype– phenotype associations from publicly available genetic association studies. inaula.corporatelearning.itWeb18. júl 2024 · We included GWAS data sources of potential mediators (obesity-related phenotypes) with maximized sample sizes but avoided sample overlap (Supplementary … in amoeba the contractile vacuole helps in