Fbw1a
WebBTRC. BETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCP, RP11-529I10.2. beta-transducin repeat containing E3 ubiquitin protein ligase. CRISPR Database OMIM VEGA HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD. WebOct 21, 1999 · As representative examples of all three classes of F-box proteins, we characterized the full-length members (Figure 2 and Supplementary material).We …
Fbw1a
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WebThe protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. This protein is homologous to Xenopus bTrCP1, yeast Met30, Neurospora Scon2 and Drosophila Slimb proteins. It interacts with HIV-1 Vpu and connects CD4 to the proteolytic machinery. WebBTRCP / BETA-TRCP beta-transducin repeat containing E3 ubiquitin protein ligase. Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
WebMar 21, 2024 · Entrez Gene Summary for BTRC Gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the …
WebProtein: FOXN3 Forkhead box protein N3 (Checkpoint suppressor 1) Gene: FOXN3 Organism: Homo sapiens Interactions: 48 UniProt ID: O00409 Gene Ontology (top 5): GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000987 - cis-regulatory region sequence-specific DNA … WebAs a first step aimed at determining if FBP genes could be involved in human neoplasia, we have mapped the chromosome positions of 5 FBP genes by fluorescence in situ hybridization (FISH) to 10q24 (BTRC alias beta-TRCP/FBW1a), 9q34 (FBXW2 alias FBW2), 13q22 (FBXL3A alias FBL3a), 5p12 (FBXO4 alias FBX4) and 6q25-->q26 (FBXO5 alias …
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http://www.informatics.jax.org/marker/MGI:1338871 houtmeterWebNov 3, 2008 · ROC1-SCF Fbw1a-induced proteasomal degradation may be necessary to terminate Smad3-mediated transcriptional activity. Wan et al. reported that SCF Fbw1a also regulates Smad4 protein stability. Smad4 mutants isolated from cancer cells exhibit accelerated induction of ubiquitin-dependent proteasomal degradation in comparison to … how many genders are recognizedWebFiling Status and Exemption Form. This form must be executed in every case of Compensable Disability, For injuries occurring on or after October 1, 1991 hout merantiWebOct 21, 1999 · As representative examples of all three classes of F-box proteins, we characterized the full-length members (Figure 2 and Supplementary material).We determined whether Fbw2, Fbl3a, Fbx4 and Fbx7, like Fbw1a/β-Trcp and Fbl1/Skp2, interact with human Skp1 and Cul1 in vivo.FLAG epitope-tagged versions of wild-type … houtmeubel collegeWebβ-transducin repeat-containing protein (β-TrCP or FBW1A) is an F-box family protein characterized by the presence of the protein-protein mediating F-box domain first described in cyclin F. F-box proteins act as substrate adaptors that target proteins containing a specific phosphorylated sequence element, referred to as a phosphodegron, to the ... how many genders are there 2010WebSmad degradation regulates TGF-beta family signaling; HECT (homologous to the E6-accessory protein C-terminus)-type E3 ubiquitin ligases, Smad ubiquitin regulatory factor 1 (Smurf1), Smurf2, and a RING-type E3 ubiquitin ligase, ROC1-SCF(Fbw1a) have been implicated in Smad degradation. houtmeyers zilverspar molWebFBW1A; FBXW1; FBXW1A; FBXW1ABTRCP; FWD1; MGC4643; pIkappaBalpha-E3 receptor subunit; Background. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called … how many genders are out there